Nu-Joint reduces nitric oxide production and increases cartilage formation by combining glucosamine with supplements such as niacinamide, resveratrol and zinc.
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Nitric oxide reduces the production of new cartilage and cartilage repair.1 Niacinamide, a form of the B vitamin niacin, reduces nitric oxide production.2
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Resveratrol, a naturally occurring antioxidant abundant in grapes, and a powerful COX-2 inhibitor, also inhibits the production of nitric oxide.3
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References
- Amin AR, Abramson SB, Curr Opin Rheumatol 1998 May 10;3:263-268.
- McCarthy, Russell AL, Niacinamide therapy for osteoarthritis Medical Hypothesis 1999;53(4):350-360.
- Tsai SH, et al, Suppression of nitric oxide synthesis by resveratrol Br J Pharmacol 1999; 126(3):673-680.
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